Cenforce 130 mg tablet is an inhibitor of phosphodiesterase-5 (PDE5) chemical, which is principally used to treat erectile dysfunction and aspiratory hypertension. Sildenafil is a particular and powerful inhibitor of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum that instigates…
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What is Cenforce 130 Mg?
Cenforce 130 mg is a medicine that doctors recommend to people with problems of impotence. The patients will be able to maintain a proper erection for a longer time.
Is Cenforce 130 Mg Safe?
Cenforce 130 contains a big concentration of the drug sildenafil but it will be safe for the patient if he is taking it after getting it prescribed from a doctor.
Manufacture
Centurion Laboratories Private Limited is the company that manufactures this medicine. It manufactures and exports many pharmaceutical products like nutraceutical, pain killer, antiseptic, anti-allergic, psychiatric, and cardiovascular medicines. Centurion Laboratories provides its products to customers worldwide. It has its headquarters in Gorwa Vadodara, Gujarat in India.
Composition
Cenforce 130 mg contains the drug Sildenafil citrate which is an orally active drug, this means that its absorbability is best if it is taken orally. It was originally sold in the USA for treatment of impotence in men and then later it was introduced in India.
Storage
Store Cenforce 130 mg at room temperature preferably at a temperature below 25 degrees Celsius, away from direct heat, sunlight, and humidity inside a closed container. It can be very harmful if it is accidentally ingested by your pets and it is not for the use of children either so keep it away from them.
What is the Use of Cenforce 130 Mg?
Medical UsesÂ
Cenforce 130 mg is used to treat the problem of impotence or erectile dysfunction in men. This is the inability to manage and maintain a suitable erection for sexual activity. It is also used to relieve pulmonary hypertension and altitude sickness.
Non-Medical Uses
It was mistakenly perceived as an aphrodisiac and now even men without erectile dysfunction are using it to enhance their sexual satisfaction and pleasure.
How to Take Cenforce 130 Mg Pills?
Take Cenforce 130 mg around 30 minutes to 60 minutes before you indulge in sexual activities along with a lot of water. Do not try to crush or chief or break the medicine.
How Does Cenforce 130 Mg work?
Sildenafil selectively inhibits the action of phosphodiesterase 5 and enhances the action of nitrates in the corpus cavernosum, causes vasodilatation, and increases blood supply to the penis. Cenforce 130 mg improves the erection on sexual arousal and it has no effect in the absence of sexual activity. So, sildenafil becomes ineffective in men who have new libido or if the cause of loss of proper erection is some sort of injury.
Side Effects of Cenforce 130 MgÂ
Common Side Effects
Nausea
Coughing
Vomiting
Headaches
Nose bleeds
Prolonged erections
The feeling of weakness and confusion
Arrhythmia
Dizziness
Special flushing
Nasal congestion
Fall in blood pressure
Gastric reflux and dyspepsia
Loose motions
Fatigue
Rare Side Effects
Loss of vision
Anxiety
Bleeding in the eye
Pain in the bone and chest
Cold sweat
Convulsions or seizures
Cool and pale skin
Lack of concentration
Dryness of the mouth
Fever
Mental depression
Cenforce 130 Mg Dosages
Cenforce 130 mg is to be taken around an hour before intercourse or as recommended by your consulting medical health personnel.
Missed Dose
In the unlikely event that you have forgotten the dose, take it the moment you remember it before having sex and do not overuse the medicine to make up for what you missed.
Overdose of Cenforce 130 Mg
The most common symptoms associated with overdosing on sildenafil are painting, hot flushing, and painful prolonged erection. In case of any of the above contact the medical helpline immediately.
They reduce the adrenergic activity of the blood vessels and cause hypertension. This leads to low blood pressure.
Amlodipine
Amlodipine, being a calcium channel blocker, widens the blood vessel and reduces blood pressure. Sildenafil adds to this effect of amlodipine.
Ritonavir and Other Inhibitors of CYP3A4
CYP3A4 is a human cytochrome that metabolizes sildenafil. If it is inhibited by ritonavir or other drugs, the blood levels of sildenafil will increase.
Alcohol
Alcohol is a vasodilator just like Sildenafil. It might not be a problem if the patient takes little quantities of alcohol but taking too much of it will make the blood pressure fall yet further under the influence of Sildenafil and will produce symptoms like dizziness and confusion and heart palpitations.
Contraindication
Nitrates
Nitrates have a vasodilating action which is promoted by sildenafil and this leads to dangerous lowering of blood pressure. This can even be fatal as it causes myocardial infarction in the patient. Sildenafil remains in the blood for around a day and it is advised that the patient should not take nitrates for around three days after taking Sildenafil.
Hypersensitivity Reactions
Discontinue the use of this medicine if you find out that you are sensitive to it. The most commonly presented symptoms of hypersensitivity are flushing, abnormal vision, dyspepsia, headache, nasal congestion, back pain, myalgia, nausea, dizziness, and rashes.
Warnings and Precautions
CardiovascularÂ
Sildenafil causes a reduction in blood pressure. It is a drug of choice in patients with pulmonary arterial hypertension. But it can be fatal for patients with hypotension.Â
Prolonged Erection and Priapism
It mostly does not cause priapism but in case it happens, seek medical help quickly.
Effects on the Eye
It can make the eyes bleed, make them lose the ability to distinguish between some colors and it can even cause retinopathy.
Hearing Loss
It can lead to loss of hearing power of the patient through Sensorineural mechanisms. Talk to the doctor thoroughly about it.
How Does it React with Other PDE5 Inhibitors?
They all work similarly and there can be the toxicity of the drug if their dosage is not regulated.
Effect on Bleeding
It can cause bleeding from the eye, nose, gastrointestinal organs, etc.
Counseling Patients About Sexually Transmitted diseases
Cenforce 130 mg will not protect you from any sexually transmitted diseases and will not avoid any pregnancy.
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Cenforce 130 Mg Reviews
After taking it orally, the bioavailability of sildenafil is around 40% and the maximum concentration of blood levels is attained in one to two hours. It is recommended in men more than 65 years of age for whom 50-milligram dosage is not effective. A lot of controlled trials have confirmed the efficacy of this drug.
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