Duzelaz 40 Tablet is used in the treatment of depression, anxiety disorder, diabetic nerve pain. It contains Duloxetine which works by increasing the level of chemical messengers in your brain that have a calming effect on the brain and relax…
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What is Duzela 40?
This medicine is a newer one. It has a mild sedative effect and some antimuscarinic effects too but it won't work as an antihistamine or an alpha-blocker. It is particularly used for the treatment of diabetes and other types of neuropathic pain, fibromyalgia, stress urinary incontinence, etc. Apart from that, it has also been used for maintenance therapy in panic disorders. It is currently under research to establish its use in the treatment of pain in cancer, surgery, and many other problems.
Is Duzela 40 Safe?
Yes, this medicine is absolutely safe for use and its safety has been demonstrated by various control experiments and observations in the patients who have taken its therapy previously. But this medicine can have unwanted drug interactions with some medicines and it can be contraindicated for use in some health problems so it is better that you advise your doctor about all of them before you start taking this treatment.
Manufacturer
The manufacturer of this medicine is Sun-Pharma Laboratories. Along with this medicine, the company is a seller of varieties of medicines. USA and India are the two topmost countries where this company’s products are sold. The headquarter of this renowned pharma giant is situated in Goregaon, Mumbai. It has a couple of subsidiaries including Ranbaxy laboratories, pharmalucence, etc.Â
Composition
It has got the drug duloxetine in it in a 40-milligram concentration. This drug is classified under the chemical class of naphthalene derivatives. It is a serotonin-norepinephrine reuptake inhibitor and it is mostly used to solve the health problems that have an origin in the central nervous system of the patient. This medicine provides a very calming effect on the brain and it relaxes the nerves while it treats your diseases
Storage
You are supposed to store this medicine properly so that you can ensure the proper efficacy of this medicine. Protect It from direct heat and sunlight and humidity and put it in a cool and dry place away from the reach of your children and your pets.
What is the Use of Duzela 40?
Medical Use
This medicine is indicated for use in Depression, Anxiety disorder, Diabetic nerve pain, Fibromyalgia, Neuropathic pain, and stress urinary incontinence.
Non-Medical Uses
unless a doctor prescribed this medicine to you, it is not safe to use this medicine. Do not use it until you have a particular problem and you need it specifically.
How to Take Duzela 40 Pills?
The patient should swallow this spill whole without breaking or crushing or chewing it. The patient should also strictly adhere to the dosage schedule that the doctor has given him so that he can obtain the maximum benefit from this treatment
How Does Duzela 40 Work?
This medicine basically increases the level of the chemical messengers in the brain which are called serotonin and noradrenaline. These naturally released substances help in the maintenance of mental balance and they also work to prevent the transmission of the pain signals in the brain. This medicine also reduces nerve damage and reduces pain in Neuropathic pain by regulating neurotransmitters.
Side Effects of Duzela 40Â
Common
Nausea
Headache
Dryness in mouth
Sleepiness
Dizziness
Trouble sleeping
Rare
Decrease in thyroid gland activityÂ
Dehydration
Low levels of sodium in the blood
Psychological problems like Suicidal behavior, mania, hallucinations, aggression, and anger
Duzela 40 Dosages
The dosage of this medicine will be decided by the doctor based on your symptoms and other relevant factors. You may see noticeable changes after two to four weeks of taking this medicine regularly.
Missed Dose
Now, if this happens then it is okay to take this medicine when you remember about it but do not take it if the time for the next dose is already very near because this can lead to an overdose of this medicine which is very harmful.
Overdosage of Duzela 40
If the overdose is extremely high the patient may even die. Other symptoms of overdose of this medicine include Somnolence, coma, serotonin syndrome, seizure, syncope, hypo- or hypertension, tachycardia, and vomiting. Also, this medicine has no antidote and it cannot be cleared by hemodialysis and the only option that is left is to start gastric lavage to prevent further absorption of this medicine in the body.
Interactions
Alpha-Blocker
No interactions have been established between the two medicines
Amlodipine
A combination of these two medicines is known to increase the risk of orthostatic hypotension and syncope.
Ritonavir and Other CYP3A4 Inhibitors
The metabolism of Ritonavir can be decreased when it is taken with Duloxetine. So inform your doctor if you are taking these medicines.
Alcohol
This medicine increases the dizziness, drowsiness, and sleepiness that is caused by alcohol. Also taking this medicine along with alcohol will increase the damage risk to the liver.
Contraindication
Nitrates
No significant interactions have been established between the two medicines.
Hypersensitivity Reactions
difficulty in breathing, dizziness with swollen tongue and lips are the Indications of allergy to this medicine
Warnings and Precautions
CardiovascularÂ
Hot flushes, palpitations, abnormal heart rhythm, increased blood pressure, and orthostatic hypotension is the side effects of this medicine on the cardiovascular system.
Prolonged Erection and Priapism
This medicine does not cause prolonged painful erection and it does not treat them either.
Effects on the Eye
Eye pain, changes in vision and swelling or redness in or around the eye, dry eye, dilated pupils are the side effects of this medicine on the eyes
Hearing Loss
Ringing in the ears and earache are the side effects of this medicine on the ears
How Does it React with Other PDE 5 Inhibitors?
This medicine can decrease the metabolism of sildenafil in the body. And cause and increased action of sildenafil.
Effect on Bleeding
This medicine is not known to cause any bleeding disorders in the recipients.
Counseling Patients About Sexually Transmitted DiseasesÂ
Neither does this medicine prevent the transmission of sexually transmitted diseases nor will it protect you from unwanted pregnancies.
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